BDBM522415 8-fluoro-2-(cis-3-fluoro-3-methylcyclobutyl)-1- [(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-1H- imidazo[-c]quinoline::US11161844, Example 31
SMILES C[C@@H]1CC(CCO1)n1c(nc2cnc3ccc(F)cc3c12)C1C[C@@](C)(F)C1
InChI Key InChIKey=BZUONQULAOIALH-VNNCBBOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 522415
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 15.8nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair