BDBM523177 US11161864, Example 25D
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)OCCn3c(COP(S)(=O)O[C@@H]1[C@H]2F)nc1cncnc31
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 523177
Affinity DataIC50: <1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [154-378](Mus musculus (Mouse))
Venenum Biodesign
US Patent
Venenum Biodesign
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [155-379](Homo sapiens (Human))
Venenum Biodesign
US Patent
Venenum Biodesign
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair