BDBM523610 US11136311, Compound 99

SMILES CC(C)CCc1c(Nc2nccc(n2)-c2cc3c(NC[C@]3(C)CO)c(c2)C#N)cnn1C

InChI Key InChIKey=XNMILTRZMDSCIE-XMMPIXPASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523610   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM523610(US11136311, Compound 99)
Affinity DataIC50:  2.90nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent