BDBM523659 US11136311, Compound 149
SMILES CN(C)C(=O)c1sc(Nc2nccc(n2)-c2cc3c(NC[C@]3(C)CO)c(c2)C#N)nc1C
InChI Key InChIKey=HWNPWSGRRNIZIC-JOCHJYFZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 523659
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.700nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair