BDBM523727 US11136311, Compound 218
SMILES C[C@]1(CO)CNc2c1cc(cc2C#N)-c1ccnc(Nc2cn(CC(F)F)nc2OC2CC2)n1
InChI Key InChIKey=RNKLJWLOGGONHH-HSZRJFAPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 523727
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 2.80nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair