BDBM523756 US11136312, Compound MM-I-83

SMILES Fc1ccc2c(Cc3nnc(Cc4cccc(Br)c4)n3CCCc3c[nH]cn3)c[nH]c2c1

InChI Key InChIKey=RDBYFPGWORQRTN-UHFFFAOYSA-N

Data  7 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 523756   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  1.04nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  264nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  2.08E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  2.08E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi:  2.73E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST5 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataEC50:  0.276nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523756(US11136312, Compound MM-I-83)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed