BDBM523766 US11136312, Compound SK-I-57
SMILES COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(c4)C(F)(F)F)n3CCCc3c[nH]cn3)c2c1
InChI Key InChIKey=FWYGJAUWVCVBHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 523766
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.76nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Southern Illinois University Edwardsville
Curated by ChEMBL
Southern Illinois University Edwardsville
Curated by ChEMBL
Affinity DataKi: 365nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Southern Illinois University Edwardsville
Curated by ChEMBL
Southern Illinois University Edwardsville
Curated by ChEMBL
Affinity DataKi: 365nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.13E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.13E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.69E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataKi: 1.69E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Southern Illinois University Edwardsville
Curated by ChEMBL
Southern Illinois University Edwardsville
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST5 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Southern Illinois University Edwardsville
Curated by ChEMBL
Southern Illinois University Edwardsville
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University
US Patent
Board of Trustees of The Southern Illinois University
US Patent
Affinity DataEC50: 1nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair