BDBM523803 US11136312, Compound SK-I-132

SMILES COc1cccc(Sc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1

InChI Key InChIKey=IBFJVEXBVBFLNC-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 523803   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataKi:  0.646nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataKi:  656nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataKi:  2.88E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataKi:  2.91E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523803(US11136312, Compound SK-I-132)
Affinity DataEC50:  0.992nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent