BDBM524908 US11168095, Example 169

SMILES O=C1Nc2cccc(n2)-c2nncn2C\C=C/COc2ccc(cc12)N1CCOCC1

InChI Key InChIKey=UOEIAWMCULBMSM-UPHRSURJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524908   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM524908(US11168095, Example 169)
Affinity DataIC50: <100nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent