BDBM524950 US11168102, Example 1-18.

SMILES C[C@@H](Nc1ncnc2n(C)c(=O)c(cc12)C1=CCN(CC1)C(C)=O)c1cccc2c1OCC2(F)F

InChI Key InChIKey=JDANDXZLZHIOLF-CQSZACIVSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524950   

TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM524950(US11168102, Example 1-18.)
Affinity DataIC50:  12.8nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM524950(US11168102, Example 1-18.)
Affinity DataKd:  22nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent