BDBM525050 US11168102, Example 6.
SMILES C[C@@H](Nc1nc(C)nc2n(C)c(=O)c(cc12)C1=CCNCC1)c1cc(N)cc(c1)C(F)(F)F
InChI Key InChIKey=LFUMQZZOEOCEPA-GFCCVEGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 525050
Affinity DataIC50: 20.9nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Affinity DataKd: 17.3nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair