BDBM525070 US11168102, Example 18.

SMILES C[C@@H](Nc1nc(C)nc2n(C)c(=O)c(cc12)C1CCN(C)CC1F)c1cccc(C(F)F)c1F

InChI Key InChIKey=JYNRWFPLHLZJOL-CMQUCMFRSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525070   

TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM525070(US11168102, Example 18.)
Affinity DataIC50:  5.79nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM525070(US11168102, Example 18.)
Affinity DataKd:  16nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent