BDBM525585 US11174250, Example 3

SMILES COCOc1cc(F)c(cc1C(=O)NC(C)(C)CC(C)(C)C)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1

InChI Key InChIKey=YOZWQAYOZCWKIG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525585   

TargetP61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534](Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM525585(US11174250, Example 3)
Affinity DataIC50:  966nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM525585(US11174250, Example 3)
Affinity DataKd:  11nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent