BDBM525849 US11174254, Compound G-10
SMILES COCCOc1ccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)cc3CNC(=O)c23)cc1
InChI Key InChIKey=AYKCKFZVAMUKQO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 525849
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Yangtze River Pharmaceutical Group
US Patent
Yangtze River Pharmaceutical Group
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitory activity of compounds to be tested on wild-type EGFR kinase (Invitrogen, PV3872) was measured by z-lyte methods.The working concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:The compound was predissolved in 100% DMSO.10 mM drug stock solution was obtained by dissolution at room temperature and then gradiently diluted with...More data for this Ligand-Target Pair