BDBM525849 US11174254, Compound G-10

SMILES COCCOc1ccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)cc3CNC(=O)c23)cc1

InChI Key InChIKey=AYKCKFZVAMUKQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525849   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Yangtze River Pharmaceutical Group

US Patent
LigandPNGBDBM525849(US11174254, Compound G-10)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitory activity of compounds to be tested on wild-type EGFR kinase (Invitrogen, PV3872) was measured by z-lyte methods.The working concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Yangtze River Pharmaceutical Group

US Patent
LigandPNGBDBM525849(US11174254, Compound G-10)
Affinity DataIC50:  68nMAssay Description:The compound was predissolved in 100% DMSO.10 mM drug stock solution was obtained by dissolution at room temperature and then gradiently diluted with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent