BDBM525854 US11174254, Compound G-15
SMILES C=CC(=O)Nc1cccc(Nc2nc3CNC(=O)c3c(Nc3ccc(cc3)N3CCOCC3)n2)c1
InChI Key InChIKey=ZVAUQFPCSPQPRD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 525854
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Yangtze River Pharmaceutical Group
US Patent
Yangtze River Pharmaceutical Group
US Patent
Affinity DataIC50: 4.27E+3nMAssay Description:The inhibitory activity of compounds to be tested on wild-type EGFR kinase (Invitrogen, PV3872) was measured by z-lyte methods.The working concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:The compound was predissolved in 100% DMSO.10 mM drug stock solution was obtained by dissolution at room temperature and then gradiently diluted with...More data for this Ligand-Target Pair