BDBM526264 US11185100, TABLE 14.4

SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(Cl)ncnc12

InChI Key InChIKey=WNBYTJKDDLUPCV-KQYNXXCUSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 526264   

TargetTaste receptor type 1 member 1/3(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataEC50: >3.00E+4nMAssay Description:The concentration of alanine is 20 mM.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  87nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  129nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  741nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed