BDBM526975 8-Amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-d3)-5-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide::US11186580, Example 9::US11225486, Example 81

SMILES Cc1ccc(cc1-c1cnc2c(N)nc(cn12)C(=O)NCC(C)(C)O)C(C)(O)C(F)(F)F

InChI Key InChIKey=VHMODILVAAVUJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 526975   

LigandPNGBDBM526975(8-Amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526975(8-Amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-...)
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526975(8-Amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-...)
Affinity DataIC50: <100nMAssay Description:[γ-33]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526975(8-Amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent