BDBM527708 US11186589, Compound 24b

SMILES C[C@]1(CO)CNc2c1cc(cc2C#N)-c1ccnc(Nc2cnn3c2OCCC3(C)C)n1

InChI Key InChIKey=ZWEDMDNBMHBCDB-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527708   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM527708(US11186589, Compound 24b)
Affinity DataIC50:  4.90nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent