BDBM527708 US11186589, Compound 24b
SMILES C[C@]1(CO)CNc2c1cc(cc2C#N)-c1ccnc(Nc2cnn3c2OCCC3(C)C)n1
InChI Key InChIKey=ZWEDMDNBMHBCDB-HSZRJFAPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 527708
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 4.90nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair