BDBM527736 5-{1-(cyclopropylmethyl)-3- [2-(dimethylamino)ethyl]-2- oxo-1,3,8-triazaspiro[4.5]dec- 8-yl}-3-(1-methyl-1H- pyrazol-4-yl)pyrazine-3- carbonitrile::US11179389, Compound 1-4

SMILES CN(C)CCN1CC2(CCN(CC2)c2cnc(C#N)c(n2)-c2cnn(C)c2)N(CC2CC2)C1=O

InChI Key InChIKey=KLZSJUQYYIAVDG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527736   

LigandPNGBDBM527736(5-{1-(cyclopropylmethyl)-3- [2-(dimethylamino)ethy...)
Affinity DataIC50:  10nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent