BDBM527750 5-{3-[2- (dimethylamino)ethyl]-2-oxo- 1-(2,2,2-trifluoro-1- methylethyl)-1,3,8- triazaspiro[4.5]dec-8-yl}-3- (1-methyl-1H-pyrazol-4- yl)pyrazine-2-carbonitrile::US11179389, Compound 1-5

SMILES CC(N1C(=O)N(CCN(C)C)CC11CCN(CC1)c1cnc(C#N)c(n1)-c1cnn(C)c1)C(F)(F)F

InChI Key InChIKey=HYLDELPQQLYMRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527750   

LigandPNGBDBM527750(5-{3-[2- (dimethylamino)ethyl]-2-oxo- 1-(2,2,2-tri...)
Affinity DataIC50:  7.20nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent