BDBM527754 5-[1-(cyclopropylmethyl)-2,2- dioxido-2-thia-1,3,8- triazaspiro[4.5]dec-8-yl]-3-(1- methyl-1H-pyrazol-4- yl)pyrazine-2-carbonitrile::US11179389, Compound 1-6

SMILES Cn1cc(cn1)-c1nc(cnc1C#N)N1CCC2(CNS(=O)(=S)N2CC2CC2)CC1

InChI Key InChIKey=MLNZZZIGQUBUNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527754   

LigandPNGBDBM527754(5-[1-(cyclopropylmethyl)-2,2- dioxido-2-thia-1,3,8...)
Affinity DataIC50:  12nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent