BDBM527772 5-[1-(cylcopropylmethyl)-2- oxo-4-oxa-1,8- diazaspiro[5.5]undec-9-yl]-3- (1-methyl-1H-pyrazol-4- yl)pyrazine-2-carbonitrile::US11179389, Compound 1-24
SMILES Cn1cc(cn1)-c1nc(cnc1C#N)N1CCC2(CC1)COCC(=O)N2CC1CC1
InChI Key InChIKey=GJCMBIFMBWQXRQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 527772
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [14-604](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 10nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair