BDBM527772 5-[1-(cylcopropylmethyl)-2- oxo-4-oxa-1,8- diazaspiro[5.5]undec-9-yl]-3- (1-methyl-1H-pyrazol-4- yl)pyrazine-2-carbonitrile::US11179389, Compound 1-24

SMILES Cn1cc(cn1)-c1nc(cnc1C#N)N1CCC2(CC1)COCC(=O)N2CC1CC1

InChI Key InChIKey=GJCMBIFMBWQXRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527772   

LigandPNGBDBM527772(5-[1-(cylcopropylmethyl)-2- oxo-4-oxa-1,8- diazasp...)
Affinity DataIC50:  10nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent