BDBM527773 5-(4-methyl-4-morpholin-4- ylpiperidin-1-yl)-3-(1-methyl- 1H-pyrazol-4-yl)pyrazine-2- carbonitrile::US11179389, Compound 1-25

SMILES Cn1cc(cn1)-c1nc(cnc1C#N)N1CCC(C)(CC1)N1CCOCC1

InChI Key InChIKey=SOPPAEWCPFKGHV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527773   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [14-604](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM527773(5-(4-methyl-4-morpholin-4- ylpiperidin-1-yl)-3-(1-...)Copy SMILESCopy InChI

Affinity DataIC50:  52nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4×Reaction...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI