BDBM527781 5-[(3R)-3-methyl-4-(2-oxa-6- azaspiro[3.3]hept-6- ylcarbonyl)piperazin-1-yl]-3- (1-methyl-1H-pyrazol-4- yl)pyrazine-2-carbonitrile::US11179389, Compound 1-33

SMILES C[C@@H]1CN(CCN1C(=O)N1CC2(COC2)C1)c1cnc(C#N)c(n1)-c1cnn(C)c1

InChI Key InChIKey=VHZGLKIUNWJRDJ-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527781   

LigandPNGBDBM527781(5-[(3R)-3-methyl-4-(2-oxa-6- azaspiro[3.3]hept-6- ...)
Affinity DataIC50:  300nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent