BDBM527787 5-[(3R)-3-methyl-4- {[(1R,2R)-2- methylcyclopropyl]carbonyl} piperazin-1-yl]-3-(1H- pyrazol-4-yl)pyrazine-2- carbonitrile::US11179389, Compound 1-39

SMILES C[C@@H]1C[C@H]1C(=O)N1CCN(C[C@H]1C)c1cnc(C#N)c(n1)-c1cn[nH]c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527787   

LigandPNGBDBM527787(5-[(3R)-3-methyl-4- {[(1R,2R)-2- methylcyclopropyl...)
Affinity DataIC50:  50nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4ŚReaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent