BDBM530431 6-(4-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin- 1(2H)-one.::WO2022070068, Example 3
SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1cc(N)c(C)cn1
InChI Key InChIKey=DFZQRULZJXPFOH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530431
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 3.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair