BDBM530431 6-(4-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin- 1(2H)-one.::WO2022070068, Example 3

SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1cc(N)c(C)cn1

InChI Key InChIKey=DFZQRULZJXPFOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530431   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech

WIPO
LigandPNGBDBM530431(6-(4-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopro...)
Affinity DataIC50:  3.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed