BDBM530458 N-(2-Chloro-6-fluorophenyl)-5-fluoro-4-(3-((R*)-1-hydroxyethyl)-4-methyl-1H-pyrazol-1-y1)-2-(((S)-1,1,1-trifluoropropan-2-yl)oxy)benzamide::WO2022070069, Example 1
SMILES C[C@@H](O)c1nn(cc1C)-c1cc(O[C@@H](C)C(F)(F)F)c(cc1F)C(=O)Nc1c(F)cccc1Cl
InChI Key InChIKey=TXMAGXRBNNNWFW-NEPJUHHUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530458
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.480nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair