BDBM530458 N-(2-Chloro-6-fluorophenyl)-5-fluoro-4-(3-((R*)-1-hydroxyethyl)-4-methyl-1H-pyrazol-1-y1)-2-(((S)-1,1,1-trifluoropropan-2-yl)oxy)benzamide::WO2022070069, Example 1

SMILES C[C@@H](O)c1nn(cc1C)-c1cc(O[C@@H](C)C(F)(F)F)c(cc1F)C(=O)Nc1c(F)cccc1Cl

InChI Key InChIKey=TXMAGXRBNNNWFW-NEPJUHHUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530458   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech

WIPO
LigandPNGBDBM530458(N-(2-Chloro-6-fluorophenyl)-5-fluoro-4-(3-((R*)-1-...)
Affinity DataIC50:  0.480nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed