BDBM530461 N-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-5-fluoro-4-(3-((R*)-l-hydroxyethyl)-4-methyl-1H-pyrazol-1-yl)-2-(((S)-1,1,1-trifluoropropan-2-yl)oxy)benzamide::WO2022070069, Example 4
SMILES C[C@@H](O)c1nn(cc1C)-c1cc(O[C@@H](C)C(F)(F)F)c(cc1F)C(=O)Nc1c(C)n[nH]c1Cl
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530461
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.220nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair