BDBM530969 4-[4- (hydroxymethyl)piperidin- 1-yl]-N1-[(3R)-pyrrolidin-3- yl]-3-(1H-tetrazol-5- yl)benzene-1,2- disulfonamide::US11207312, Example 101
SMILES NS(=O)(=O)c1c(ccc(N2CCC(CO)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 530969
Affinity DataIC50: 0.0800nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 0.390nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair