BDBM532008 N-(4-{2-Amino-5-[1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]pyridin-3-yl}-3-fluorophenyl)-5-(4-methylphenyl)-4-oxo-1-(tetrahydro-2H-pyran-4-ylmethyl)-1,4-dihydropyridine-3-carboxamide methanesulfonate::US11208403, Example 85
SMILES Cc1ccc(cc1)-c1cn(CC2CCOCC2)cc(C(=O)Nc2ccc(c(F)c2)-c2cc(cnc2N)-c2cnn(c2)C2CCOCC2)c1=O
InChI Key InChIKey=YQGUQZWOHCDPTK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 532008
Affinity DataIC50: 0.400nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:A phosphorylated Axl (hereinafter, referred to as pAxl) inhibition test was conducted using a human non-small cell lung cancer-derived cell line NCI-...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair