BDBM532542 N,N-Dimethyl-2-[6-[5-(trifluoromethyl)-2-thienyl]pyrazolo[3,4-b]pyrazin-1-::US11214563, Example 3

SMILES CN(C)C(=O)Cn1ncc2ncc(nc12)-c1ccc(s1)C(F)(F)F

InChI Key InChIKey=IMHDZWHPHBMGIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532542   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532542(N,N-Dimethyl-2-[6-[5-(trifluoromethyl)-2-thienyl]p...)
Affinity DataIC50:  581nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent