BDBM5331 1-(3-{[2-(2-oxo-1,2-dihydroquinolin-3-yl)-1H-indol-5-yl]oxy}propyl)piperidine-4-carboxylic acid::indolyl quinolinone deriv. 8

SMILES OC(=O)C1CCN(CCCOc2ccc3[nH]c(cc3c2)-c2cc3ccccc3[nH]c2=O)CC1

InChI Key InChIKey=UMILXTHDUASSHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5331   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM5331(1-(3-{[2-(2-oxo-1,2-dihydroquinolin-3-yl)-1H-indol...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed