BDBM533219 US10626094, Example I149::US11220486, Compound I149::US11220486, Compound I168::{2-[2,4-bis(trifluoromethyl)phenyl](4- quinolyl)}(3-piperidylpropyl)amine

SMILES FC(F)(F)c1ccc(-c2cc(NCCCC3CCCNC3)c3ccccc3n2)c(c1)C(F)(F)F

InChI Key InChIKey=TZAKWJYJSHUJKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 533219   

TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
La Jolla Institute of Allergy & Immunology

US Patent
LigandPNGBDBM533219(US10626094, Example I149 | US11220486, Compound I1...)
Affinity DataIC50:  500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533219(US10626094, Example I149 | US11220486, Compound I1...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533219(US10626094, Example I149 | US11220486, Compound I1...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
La Jolla Institute of Allergy & Immunology

US Patent
LigandPNGBDBM533219(US10626094, Example I149 | US11220486, Compound I1...)
Affinity DataIC50:  500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent