BDBM533743 N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide ::US11225469, Compound 267

SMILES Cc1cc(C)nc(NC(=S)N2CCC(Cc3ccc(cc3)C(F)(F)F)CC2)c1

InChI Key InChIKey=QCISZOJVNOGGFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533743   

TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533743(N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl...)
Affinity DataIC50: <5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent