BDBM533743 N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide ::US11225469, Compound 267
SMILES Cc1cc(C)nc(NC(=S)N2CCC(Cc3ccc(cc3)C(F)(F)F)CC2)c1
InChI Key InChIKey=QCISZOJVNOGGFD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 533743
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: <5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair