BDBM534124 6-(Azetidin-1-yl)-N-((2-((2,2-difluorocyclopropyl)methoxy)-5-isopropylphenyl)sulfonyl)-4-fluorobenzofuran-2-carboxamide (rac)::WO2022081807, Example 231

SMILES CC(C)c1ccc(OCC2CC2(F)F)c(c1)S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1

InChI Key InChIKey=IZSRWXZPTJHJPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534124   

TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534124(6-(Azetidin-1-yl)-N-((2-((2,2-difluorocyclopropyl)...)
Affinity DataIC50:  29nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534124(6-(Azetidin-1-yl)-N-((2-((2,2-difluorocyclopropyl)...)
Affinity DataIC50:  4.22nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed