BDBM53421 4-Cyclohexyl-2-phenyl-quinazoline::4-cyclohexyl-2-phenylquinazoline::MLS001049987::Menadione, 11::SMR000469604::cid_23640938

SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=PZXJVBUHBNWQIT-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 53421   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  7.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  600nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  600nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of UCHL1 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataEC50:  2.16E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay