BDBM53441 MLS001000876::N-(1H-benzimidazol-2-yl)-3-chloranyl-benzamide::N-(1H-benzimidazol-2-yl)-3-chloro-benzamide::N-(1H-benzimidazol-2-yl)-3-chlorobenzamide::N-1H-benzimidazol-2-yl-3-chlorobenzamide::O-acyl oxime isatin derivative, 30::SMR000497507::cid_898010

SMILES Clc1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1

InChI Key InChIKey=NNOLHIYETJFEDS-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 53441   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataKi:  400nM ΔG°:  -8.72kcal/mole IC50:  880nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataIC50:  2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataIC50:  2.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed