BDBM534436 WO2022086828, Example 172

SMILES Cc1ccc(cc1)[C@H](O)C(F)(F)CNC(=O)c1c(Cl)ccc(c1F)-c1ccn2nc(N)nc2c1

InChI Key InChIKey=ZUOVJSWGLBRILC-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534436   

TargetMixed lineage kinase domain-like protein(Homo sapiens)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534436(WO2022086828, Example 172)
Affinity DataIC50:  1.30nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed