BDBM5346 5-phenyl-N-(pyrimidin-2-yl)-1,3-thiazol-2-amine::aminothiazole 6

SMILES N(c1ncc(s1)-c1ccccc1)c1ncccn1

InChI Key InChIKey=MGPBMEUPZDYHAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5346   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM5346(5-phenyl-N-(pyrimidin-2-yl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50:  137nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed