BDBM536218 US11242344, Example 107.2::US11242344, Example 107.3

SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)C(C)(C)N1)c1cc(C)no1

InChI Key InChIKey=VEGOWGIYNZHSAH-YRGRVCCFSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 536218   

LigandPNGBDBM536218(US11242344, Example 107.2 | US11242344, Example 10...)
Affinity DataIC50:  2.41E+4nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536218(US11242344, Example 107.2 | US11242344, Example 10...)
Affinity DataKd: >1.50E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536218(US11242344, Example 107.2 | US11242344, Example 10...)
Affinity DataIC50: >5.00E+4nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536218(US11242344, Example 107.2 | US11242344, Example 10...)
Affinity DataKd:  1.49E+4nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent