BDBM536365 2-(2'-ethyl-5'-fluoro-4'-((6- (methylsulfonyl)-2,6- diazaspiro[3.3]heptan-2-yl)methyl)- [1,1'-biphenyl]-4-yl)-1,1,1,3,3,3- hexafluoropropan-2-ol::US11242350, Example 36

SMILES CCc1cc(CN2CC3(C2)CN(C3)S(C)(=O)=O)c(F)cc1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SWDYXNSGLCCVEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536365   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Escalier Biosciences

US Patent
LigandPNGBDBM536365(2-(2'-ethyl-5'-fluoro-4'-((6- (methylsulfonyl)-2,6...)
Affinity DataIC50: <50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent