BDBM537069 US11247971, Cmpd ID 392

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2cccc(c2)N2CCC(CC2)C(F)(F)F)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=ILTATVLBOVAJOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537069   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537069(US11247971, Cmpd ID 392)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of LDHA in human MIA PaCa2 cells assessed as reduction in lactate production incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537069(US11247971, Cmpd ID 392)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed