BDBM5406 2,4-Disubstituted Pyrimidine 5h::N-(3,5-dimethylphenyl)-4-(2-methyl-1H-imidazol-1-yl)pyrimidin-2-amine
SMILES Cc1nccn1-c1ccnc(Nc2cc(C)cc(C)c2)n1
InChI Key InChIKey=QPFWVFPJLHQHCT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 5406
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 765nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair