BDBM541393 US11267803, Example 41

SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CNC(=O)OCc1ccccc1)NC(=O)c1ccc2ccccc2c1)C(=O)NC1(CCCCC1)C(=O)C(N)=O

InChI Key InChIKey=QHZXLDKXLNKNOU-YPKYBTACSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541393   

TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541393(US11267803, Example 41)
Affinity DataIC50:  68nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent