BDBM541689 US11267811, Example A19

SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=SREQODHFJAFKPS-WHCFWRGISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 541689   

TargetGalectin-3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541689(US11267811, Example A19)
Affinity DataIC50:  68nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-3(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541689(US11267811, Example A19)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of His-tagged recombinant mouse Gal-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGalectin-3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541689(US11267811, Example A19)
Affinity DataIC50:  73nMAssay Description:Inhibition of His-tagged recombinant human Gal-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed