BDBM542002 1-[4-(4-fluorophenyl)-2-(triazol-2-yl)cyclopentyl]piperidin- 3-amine::US11274091, Example 1

SMILES NC1CCCN(C1)C1CC(CC1n1nccn1)c1ccc(F)cc1

InChI Key InChIKey=KFJNTKXUHMJOFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542002   

TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542002(1-[4-(4-fluorophenyl)-2-(triazol-2-yl)cyclopentyl]...)
Affinity DataIC50:  17.7nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542002(1-[4-(4-fluorophenyl)-2-(triazol-2-yl)cyclopentyl]...)
Affinity DataIC50:  3.37nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent