BDBM544540 US11286268, Compound 132::US11286268, Compound 23

SMILES CNC(=O)c1cc2c(cn1)ncn(CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)c2=O

InChI Key InChIKey=WQEFKHZIYVEKDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 544540   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM544540(US11286268, Compound 23 | US11286268, Compound 132)
Affinity DataIC50: 624nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM544540(US11286268, Compound 23 | US11286268, Compound 132)
Affinity DataIC50: 624nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent