BDBM544997 US11286268, Compound 482

SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

InChI Key InChIKey=MOFUDXQVPWIFAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 544997   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM544997(US11286268, Compound 482)
Affinity DataIC50: 35.4nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent