BDBM545156 US11286268, Compound 642

SMILES C[C@H]1CN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)C[C@@H](C)O1

InChI Key InChIKey=RJWMRXDFSBCQIX-KDURUIRLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545156   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM545156(US11286268, Compound 642)
Affinity DataIC50:  3.63nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent