BDBM545156 US11286268, Compound 642
SMILES C[C@H]1CN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)C[C@@H](C)O1
InChI Key InChIKey=RJWMRXDFSBCQIX-KDURUIRLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 545156
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics
US Patent
Effector Therapeutics
US Patent
Affinity DataIC50: 3.63nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair