BDBM545381 US11286268, Compound 870

SMILES Cc1cnc(C)c(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

InChI Key InChIKey=NQKJPFRBDIIZFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545381   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM545381(US11286268, Compound 870)
Affinity DataIC50: 140nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent